Anti-Histone H3 Monoclonal Antibody

Conjugation :

Unconjugation

Host :

Mouse

Clonality :

Monoclonal Antibody

Gene symbol :

Histone H3

Immunogen :

Recombinant Protein

Synonym :

HIST1H3J;H3/j;H3FJ

Isotype :

IgG1

Gene ID :

8290

Clone No :

1G1

Swiss Port :

P68431

Molecular weight :

15kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat Yeast

Application :

WB IHC IP IF

Recommended dilution :

WB 1:1000-3000. IHC 1:100-300.

Subcellular location :

Nucleus

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.