Anti-TESC Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

TESC

Immunogen :

Recombinant protein of human TESC

Synonym :

CHP3;TSC;tescalcin

Isotype :

IgG

Gene ID :

54997

Clone No :

Swiss Port :

Q96BS2

Molecular weight :

19/21/25kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB

Recommended dilution :

WB 1:1000-3000.

Subcellular location :

Nucleus Cell membrane

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.