Anti-ATP6AP2 Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

ATP6AP2

Immunogen :

A synthetic peptide of Human ATP6AP2

Synonym :

APT6M8-9;ATP6IP2;ATP6M8-9;ELDF10;HT028;M8-9;MRXE;MRXSH;MSTP009;PRR;RENR;XMRE;XPDS

Isotype :

IgG

Gene ID :

10159

Clone No :

Swiss Port :

O75787

Molecular weight :

36/39kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB IHC

Recommended dilution :

WB 1:1000-3000. IHC 1:50-200.

Subcellular location :

Cytoplasm

Storage :

Store at -20～C. Avoid freeze / thaw cycles.

Background :

Multifunctional protein which functions as a renin, prorenin cellular receptor and is involved in the assembly of the proton-transporting vacuolar (V)-ATPase protein pump. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS). Probably by controlling the assembly of the V-ATPase pump and thus the acidification of the endo-lysosomal system, plays a role in many neuronal processes including synapse morphology and synaptic transmission.