Anti-SYT1/2 Polyclonal Antibody

No :   K108669P
Size :   
Quantity :   
PRODUCT DESCRIPTION

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

SYT1/2

Immunogen :

A synthetic peptide of Human SYT1/2

Synonym :

P65;SVP65;SYT;synaptotagmin-1

Isotype :

IgG

Gene ID :

6857/127833

Clone No :

Swiss Port :

P21579/Q8N9I0

Molecular weight :

47kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat Cow

Application :

IHC

Recommended dilution :

IHC 1:25-100.

Subcellular location :

Cytoplasm Nucleus

Storage :

Store at -20~C. Avoid freeze / thaw cycles.

Background :

Calcium sensor that participates in triggering neurotransmitter release at the synapse. May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner; these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes.
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