Anti-DCTN3 Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

DCTN3

Immunogen :

Recombinant protein of human DCTN3

Synonym :

DCTN-22

Isotype :

IgG

Gene ID :

11258

Clone No :

Swiss Port :

O75935

Molecular weight :

18/21kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB IHC

Recommended dilution :

WB 1:1000-3000. IHC1:50-200.

Subcellular location :

Cytoplasm

Storage :

Store at -20～C. Avoid freeze / thaw cycles.

Background :

This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants.