PRODUCT DESCRIPTION
Species :
RatAssay Type :
Solid Phase Sandwich ELISASensitivity :
10 pg/mlDetection Range :
56-3600 pg/mlAssay Length :
3.5hSample Type :
Serum; Plasma; Cell culture supernatant.Long Name :
Cyclooxygenase 2Synonyms :
COX2; COX-2; COX2cyclooxygenase 2b; cyclooxygenase-2; GRIPGHS; hCox-2; PGG/HS; PGH synthase 2; PGHS-2; PHS II; PHS-2; PHS-II; prostaglandin G/H synthase 2; prostaglandin G/H synthase and cyclooxygenase; Prostaglandin H2 synthase 2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase andcyclooxygenase); Prostaglandin-endoperoxide synthase 2; PTGS2Background :
Cyclooxygenase (COX), also known as prostaglandin G/H synthase, is a membrane bound enzyme partly responsible for the catalysis of prostanoid synthesis. COX is expressed as at least three different isoforms. COX-1 is constitutively expressed and thought to regulate a number of 'housekeeping' functions such as vascular hemostasis, renal blood flow, and glomerular function. COX-2 expression is tightly regulated and induced by inflammatory mediators such as growth factors, cytokines, and endotoxin. COX-3 appears to be much more strictly regulated spatially and is observed in greatest abundance in cerebral cortex.RELATED PRODUCTS
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REFERENCE LIBRARY
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