Anti-HTR2B Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

HTR2B

Immunogen :

Recombinant protein of human HTR2B

Synonym :

5-HT(2B);5-HT-2B;5-HT2B

Isotype :

IgG

Gene ID :

3357

Clone No :

Swiss Port :

P41595

Molecular weight :

54kDa

Purification :

Affinity purification

Reactivity :

Human

Application :

WB IHC

Recommended dilution :

WB 1:200-1000. IHC 1:10-100.

Subcellular location :

Cell junction Cell membrane Multi-pass membrane protein synapse synaptosome

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved.