Anti-TLR1 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

TLR1

Immunogen :

Recombinant protein of human TLR1

Synonym :

CD281;TIL;TIL. LPRS5;rsc786;TIL.LPRS5;toll-like receptor 1

Isotype :

IgG

Gene ID :

7096

Clone No :

Swiss Port :

Q15399

Molecular weight :

90kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

WB IHC

Recommended dilution :

WB 1:200-1000. IHC 1:15-50.

Subcellular location :

Nucleus Cytoplasm

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.