PRODUCT DESCRIPTION
Conjugation :
UnconjugateHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
STAT4Immunogen :
Recombinant protein of human STAT4Synonym :
SLEB11Isotype :
IgGGene ID :
6775Clone No :
Swiss Port :
Q14765Molecular weight :
86kDaPurification :
Affinity purificationReactivity :
Human MouseApplication :
WB IHCRecommended dilution :
WB 1:200-1000. IHC 1:25-100.Subcellular location :
Cytoplasm NucleusStorage :
Store at -20°C. Avoid freeze / thaw cycles.Background :
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.RELATED PRODUCTS
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REFERENCE LIBRARY
No data