Anti-CASP9 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

CASP9

Immunogen :

Recombinant protein of human CASP9

Synonym :

APAF-3;APAF3;ICE-LAP6;MCH6;PPP1R56;Caspase 9

Isotype :

IgG

Gene ID :

842

Clone No :

Swiss Port :

P55211

Molecular weight :

17/30/37/46kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

WB IHC

Recommended dilution :

WB 1:500-2000. IHC 1:25-100.

Subcellular location :

Cytosol Nucleus

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms.