PRODUCT DESCRIPTION
Conjugation :
UnconjugateHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
AFPImmunogen :
Recombinant protein of human AFPSynonym :
AFPD;FETA;HPAFP;HPAFP;alpha 1 FetoproteinIsotype :
IgGGene ID :
174Clone No :
Swiss Port :
P02771Molecular weight :
69kDaPurification :
Affinity purificationReactivity :
Human Mouse RatApplication :
WB IHCRecommended dilution :
WB 1:1000-5000. IHC 1:50-200.Subcellular location :
secretedStorage :
Store at -20°C. Avoid freeze / thaw cycles.Background :
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.RELATED PRODUCTS
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REFERENCE LIBRARY
No data