Anti-AFP Polyclonal Antibody

No :   K008067P
Size :   
Quantity :   
PRODUCT DESCRIPTION

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

AFP

Immunogen :

Recombinant protein of human AFP

Synonym :

AFPD;FETA;HPAFP;HPAFP;alpha 1 Fetoprotein

Isotype :

IgG

Gene ID :

174

Clone No :

Swiss Port :

P02771

Molecular weight :

69kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB IHC

Recommended dilution :

WB 1:1000-5000. IHC 1:50-200.

Subcellular location :

secreted

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
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REFERENCE LIBRARY
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