Anti-HNF4A Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

HNF4A

Immunogen :

A synthetic peptide of human HNF4A

Synonym :

TCF;HNF4;MODY;FRTS4;MODY1;NR2A1;TCF14;HNF4a7;HNF4a8;HNF4a9;NR2A21;HNF4alpha

Isotype :

IgG

Gene ID :

3172

Clone No :

Swiss Port :

P41235

Molecular weight :

53/47/56/50/44kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB IHC

Recommended dilution :

WB 1:500-2000. IHC 1:10-100.

Subcellular location :

Nucleus

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.