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Monkey IGF-1 Elisa Kit

Long Name: Insulin-like Growth Factor I
NO.:SEKMY-0048
Quantity: 10

Information

Assay Type: Solid Phase Sandwich ELISA
Sensitivity: 10 pg/ml
Detection Range: 50-3200 pg/ml
Assay Length: 2.5h
Sample Type: Serum; Plasma; Cell culture supernatant.
Synonyms: IBP1; IGF1; IGF-1; IGF1A; IGFI; IGF-I; IGF-IA; IGF-IB; MGF; Somatomedin A; Somatomedin C;

Background

Insulin-like growth factor (IGF)-I (also known as somatomedin C and somatomedin A) and IGF-II (multiplication stimulating activity or MSA) belong to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGF-I and IGF-II share approximately 70% sequence identity. Both IGF-I and IGF-II are expressed in many tissues and cell types and may have autocrine, paracrine and endocrine functions. Mature IGF-I and IGF-II are highly conserved between the human, bovine and porcine proteins (100% identity), and exhibit cross-species activity. The IGFL (insulin-like growth factor-like) family includes four small (~11 kDa), probably secreted family members in humans and one in mouse. This family shares A and B chain cysteine motifs with the IGF superfamily, and has an additional cysteine motif within an uncleaved region corresponding to the C peptide of the IGF family.