Anti-MECOM Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

MECOM

Immunogen :

A synthetic peptide of human MECOM

Synonym :

EVI1;MDS1;KMT8E;PRDM3;RUSAT2;MDS1-EVI1;AML1-EVI-1

Isotype :

IgG

Gene ID :

2122

Clone No :

Swiss Port :

Q03112

Molecular weight :

118kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

WB IHC

Recommended dilution :

WB 1:200-1000. IHC 1:30-150.

Subcellular location :

Nucleus

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.