Anti-IL17A Polyclonal Antibody

No :   K008040P
Size :   
Quantity :   
PRODUCT DESCRIPTION

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

IL17A

Immunogen :

A synthetic peptide of human IL17A

Synonym :

IL17;CTLA8;IL-17;CTLA-8;IL-17A

Isotype :

IgG

Gene ID :

3605

Clone No :

Swiss Port :

Q16552

Molecular weight :

18kDa

Purification :

Affinity purification

Reactivity :

Human

Application :

WB IHC

Recommended dilution :

WB 1:500-2000. IHC 1:30-150.

Subcellular location :

Secreted

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
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REFERENCE LIBRARY
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