PRODUCT DESCRIPTION
Conjugation :
UnconjugateHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
IL17AImmunogen :
A synthetic peptide of human IL17ASynonym :
IL17;CTLA8;IL-17;CTLA-8;IL-17AIsotype :
IgGGene ID :
3605Clone No :
Swiss Port :
Q16552Molecular weight :
18kDaPurification :
Affinity purificationReactivity :
HumanApplication :
WB IHCRecommended dilution :
WB 1:500-2000. IHC 1:30-150.Subcellular location :
SecretedStorage :
Store at -20°C. Avoid freeze / thaw cycles.Background :
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.RELATED PRODUCTS
No data
REFERENCE LIBRARY
No data