Anti-DUSP5 Polyclonal Antibody

No :   K008035P
Size :   
Quantity :   
PRODUCT DESCRIPTION

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

DUSP5

Immunogen :

A synthetic peptide of human DUSP5

Synonym :

DUSP;HVH3

Isotype :

IgG

Gene ID :

1847

Clone No :

Swiss Port :

Q16690

Molecular weight :

42kDa

Purification :

Affinity purification

Reactivity :

Human Rat

Application :

WB IHC ELISA

Recommended dilution :

WB 1:200-1000. IHC 1: 20-100.

Subcellular location :

Cytoplasm

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.
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