Anti-DNAJC2 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

DNAJC2

Immunogen :

A synthetic peptide of human DNAJC2

Synonym :

ZRF1;ZUO1;MPP11;MPHOSPH11

Isotype :

IgG

Gene ID :

27000

Clone No :

Swiss Port :

Q99543

Molecular weight :

72/66kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

IHC

Recommended dilution :

IHC 1:30-150.

Subcellular location :

Cytoplasm Nucleus cytosol

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.