Anti-ITGAV Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

ITGAV

Immunogen :

A synthetic peptide of human ITGAV

Synonym :

CD51;MSK8;VNRA;VTNR

Isotype :

IgG

Gene ID :

3685

Clone No :

Swiss Port :

P06756

Molecular weight :

116/112kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

IHC

Recommended dilution :

IHC 1:50-100.

Subcellular location :

Cytoplasm Membrane

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.