Anti-MAGEB18 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

MAGEB18

Immunogen :

A synthetic peptide of human MAGEB18

Synonym :

MAGE-B18 antigen;Melanoma-associated antigen B18

Isotype :

IgG

Gene ID :

286514

Clone No :

Swiss Port :

Q96M61

Molecular weight :

39kDa

Purification :

Affinity purification

Reactivity :

Human

Application :

WB

Recommended dilution :

WB 1:200-1000.

Subcellular location :

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors and, based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens that are expressed in tumors of different histologic types and in normal testis and placenta. MAGE-B18 (melanoma-associated antigen B18) is a 343 amino acid protein that contains one MAGE domain and may be involved in tumorigenesis. The gene encoding MAGE-B18 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes.