Anti-IGF1R Polyclonal Antibody

No :   K007958P
Size :   
Quantity :   
PRODUCT DESCRIPTION

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

IGF1R

Immunogen :

A synthetic peptide of human IGF1R

Synonym :

IGFR;CD221;IGFIR;JTK13

Isotype :

IgG

Gene ID :

3480

Clone No :

Swiss Port :

P08069

Molecular weight :

67/114kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

IHC

Recommended dilution :

IHC 1:20-100.

Subcellular location :

Cell membrane Single-pass type I membrane protein

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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REFERENCE LIBRARY
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