PRODUCT DESCRIPTION
Conjugation :
UnconjugateHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
IGF1RImmunogen :
A synthetic peptide of human IGF1RSynonym :
IGFR;CD221;IGFIR;JTK13Isotype :
IgGGene ID :
3480Clone No :
Swiss Port :
P08069Molecular weight :
67/114kDaPurification :
Affinity purificationReactivity :
Human Mouse RatApplication :
IHCRecommended dilution :
IHC 1:20-100.Subcellular location :
Cell membrane Single-pass type I membrane proteinStorage :
Store at -20°C. Avoid freeze / thaw cycles.Background :
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.RELATED PRODUCTS
No data
REFERENCE LIBRARY
No data