Anti-BIRC7 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

BIRC7

Immunogen :

A synthetic peptide of human BIRC7

Synonym :

KIAP;LIVIN;MLIAP;RNF50;ML-IAP

Isotype :

IgG

Gene ID :

79444

Clone No :

Swiss Port :

Q96CA5

Molecular weight :

33kDa

Purification :

Affinity purification

Reactivity :

Human

Application :

IHC

Recommended dilution :

IHC 1:25-100.

Subcellular location :

Cytoplasm Golgi apparatus Nucleus

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants