Anti-NANOS1 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

NANOS1

Immunogen :

A synthetic peptide of human NANOS1

Synonym :

NOS1;SPGF12

Isotype :

IgG

Gene ID :

340719

Clone No :

Swiss Port :

Q8WY41

Molecular weight :

30kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

WB

Recommended dilution :

WB 1:500-2000.

Subcellular location :

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

Nanos1, also known as NOS1, is a 292 amino acid protein that localizes to the perinuclear region of the cytoplasm and contains one nanos-type zinc finger. Expressed at high levels in spermatogonia and present at lower levels in fetal ovaries, Nanos1 forms a complex with Pumilio 2 and functions to regulate the translation of select mRNAs, specifically via association with the 3’-UTR of its mRNA targets. Additionally, Nanos1 is required for the establishment and maintenance of germline stem cells, as it prevents their premature entry into oogenesis.