Anti-HNF1A Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

HNF1A

Immunogen :

A synthetic peptide of human HNF1A

Synonym :

HNF1;LFB1;TCF1;MODY3;TCF-1;HNF-1A;IDDM20

Isotype :

IgG

Gene ID :

6927

Clone No :

Swiss Port :

P20823

Molecular weight :

67kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB IHC

Recommended dilution :

WB 1:500-2000. IHC 1:25-100.

Subcellular location :

Nucleus

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.