Anti-TRIM71 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

TRIM71

Immunogen :

A synthetic peptide of human TRIM71

Synonym :

LIN41;LIN-41

Isotype :

IgG

Gene ID :

131405

Clone No :

Swiss Port :

Q2Q1W2

Molecular weight :

93kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB ELISA

Recommended dilution :

WB 1:1000-5000.

Subcellular location :

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

LIN-41, also called tripartite motif-containing 71 (TRIM71), which was first identified in Caenorhabditis elegans, is responsible for the timing of cell fate determination. By encoding microRNAs (miRNAs), the heterochronic genes let-7 and lin-4 downregulate the gene encoding LIN-41. The miRNAs bind to six complementary sites on the 3' untranslated region (UTR) of the LIN-41 gene. This downregulation positively regulates the timing of the expression of LIN-29, an adult specification transcription factor.