Anti-SLC17A1 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

SLC17A1

Immunogen :

A synthetic peptide of human SLC17A1

Synonym :

NPT1;NPT-1;NAPI-1

Isotype :

IgG

Gene ID :

6568

Clone No :

Swiss Port :

Q14916

Molecular weight :

51kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB

Recommended dilution :

WB 1:500-2000.

Subcellular location :

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

NPT1, also called sodium-dependent phosphate transport protein, belongs to the organic anion transporter family, SLC17A. It is mainly expressed in the kidney transporting small organic anions such as PAH (para-aminohippurate), but it is also found in the liver and brain. NTP1 localizes to the apical membrane of renal proximal tubular cells and functions as a voltage driven organic anion/Cl-exchanger. It also plays a role in maintaining phosphate homeostasis. The expression of NPT1 is transcriptionally regulated by HNF-1 and HNF-3∫. Indomethacin and salicylate inhibit NPT1-mediated PAH transport.