PRODUCT DESCRIPTION
Conjugation :
UnconjugateHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
ACTN2Immunogen :
A synthetic peptide of human ACTN2Synonym :
CMD1AA;CMH23Isotype :
IgGGene ID :
88Clone No :
Swiss Port :
P35609Molecular weight :
104kDaPurification :
Affinity purificationReactivity :
Human Mouse RatApplication :
WBRecommended dilution :
WB 1:500-2000.Subcellular location :
Cytoplasm Z line myofibril sarcomereStorage :
Store at -20°C. Avoid freeze / thaw cycles.Background :
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.RELATED PRODUCTS
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REFERENCE LIBRARY
No data