Anti-ACTN2 Polyclonal Antibody

No :   K007819P
Size :   
Quantity :   
PRODUCT DESCRIPTION

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

ACTN2

Immunogen :

A synthetic peptide of human ACTN2

Synonym :

CMD1AA;CMH23

Isotype :

IgG

Gene ID :

88

Clone No :

Swiss Port :

P35609

Molecular weight :

104kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB

Recommended dilution :

WB 1:500-2000.

Subcellular location :

Cytoplasm Z line myofibril sarcomere

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.
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