Anti-RYR1 Polyclonal Antibody

No :   K007816P
Size :   
Quantity :   
PRODUCT DESCRIPTION

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

RYR1

Immunogen :

A synthetic peptide of human RYR1

Synonym :

CCO;MHS;RYR;MHS1;RYDR;SKRR;RYR-1;PPP1R137

Isotype :

IgG

Gene ID :

6261

Clone No :

Swiss Port :

P21817

Molecular weight :

565kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB

Recommended dilution :

WB 1:200-1000.

Subcellular location :

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This gene encodes a ryanodine receptor found in skeletal muscle. The encoded protein functions as a calcium release channel in the sarcoplasmic reticulum but also serves to connect the sarcoplasmic reticulum and transverse tubule. Mutations in this gene are associated with malignant hyperthermia susceptibility, central core disease, and minicore myopathy with external ophthalmoplegia. Alternatively spliced transcripts encoding different isoforms have been described.
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REFERENCE LIBRARY
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