Anti-RNLS Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

RNLS

Immunogen :

A synthetic peptide of human RNLS

Synonym :

C10orf59;RENALASE

Isotype :

IgG

Gene ID :

55328

Clone No :

Swiss Port :

Q5VYX0

Molecular weight :

38kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB

Recommended dilution :

WB 1:500-2000.

Subcellular location :

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

Renalase is a flavin adenine dinucleotide-dependent amine oxidase that is secreted into the blood from the kidney. Catalyzes the oxidation of the less abundant alpha-NAD(P)H isoform toform beta-NAD(P)+. The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk.