Anti-RCC1 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

RCC1

Immunogen :

A synthetic peptide of human RCC1

Synonym :

CHC1;RCC1-I;SNHG3-RCC1

Isotype :

IgG

Gene ID :

1104

Clone No :

Swiss Port :

P18754

Molecular weight :

45kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

WB ELISA

Recommended dilution :

WB 1:500-2000.

Subcellular location :

Cytoplasm Nucleus

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

RCC1 (regulator of chromosome condensation 1), increases the rate at which Ran exchanges GDP for GTP. Ran GAP1 opposes the effects of RCC1 by increasing the rate at which Ran hydrolyzes GTP to GDP. A protein designated Ran BP1 has no intrinsic GAP activity and functions as a GEF inhibitor, deactivating RCC1 and thereby indirectly increasing the ratio of Ran GDP to Ran GTP. Ran BP2 has been proposed as the Ran GTP docking site at the periphery of the nuclear pore complex.