Anti-TNFRSF11A Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

TNFRSF11A

Immunogen :

A synthetic peptide of human TNFRSF11A

Synonym :

FEO;OFE;ODFR;OSTS;PDB2;RANK;CD265;OPTB7;TRANCER;LOH18CR1

Isotype :

IgG

Gene ID :

8792

Clone No :

Swiss Port :

Q9Y6Q6

Molecular weight :

66kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

WB

Recommended dilution :

WB 1:200-1000.

Subcellular location :

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone.