Anti-ATP2A1 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

ATP2A1

Immunogen :

A synthetic peptide of human ATP2A1

Synonym :

ATP2A;SERCA1

Isotype :

IgG

Gene ID :

487

Clone No :

Swiss Port :

O14983

Molecular weight :

110kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

IHC

Recommended dilution :

IHC 1:25-100.

Subcellular location :

Cytoplasm

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.