Anti-IRF4 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

IRF4

Immunogen :

A synthetic peptide of human IRF4

Synonym :

LSIRF;MUM1;NF-EM5;SHEP8

Isotype :

IgG

Gene ID :

3662

Clone No :

Swiss Port :

Q15306

Molecular weight :

52kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

WB

Recommended dilution :

WB 1:200-1000.

Subcellular location :

Nucleus

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.