PRODUCT DESCRIPTION
Conjugation :
UnconjugateHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
IGF2RImmunogen :
A synthetic peptide of human IGF2RSynonym :
MPR1;MPRI;CD222;CIMPR;M6P-RIsotype :
IgGGene ID :
3482Clone No :
Swiss Port :
P11717Molecular weight :
274kDaPurification :
Affinity purificationReactivity :
Human MouseApplication :
WB IHCRecommended dilution :
WB 1:200-1000. IHC 1:50-200.Subcellular location :
CytoplasmStorage :
Store at -20°C. Avoid freeze / thaw cycles.Background :
This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.RELATED PRODUCTS
No data
REFERENCE LIBRARY
No data