Anti-HRG Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

HRG

Immunogen :

A synthetic peptide of human HRG

Synonym :

HPRG;HRGP;THPH11

Isotype :

IgG

Gene ID :

3273

Clone No :

Swiss Port :

P04196

Molecular weight :

60kDa

Purification :

Affinity purification

Reactivity :

Human

Application :

IHC

Recommended dilution :

IHC 1:25-100.

Subcellular location :

Secreted Cytoplasm

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.