Anti-HMGCS2 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

HMGCS2

Immunogen :

A synthetic peptide of human HMGCS2

Synonym :

HMG-CoA synthase

Isotype :

IgG

Gene ID :

3158

Clone No :

Swiss Port :

P54868

Molecular weight :

57kDa

Purification :

Affinity purification

Reactivity :

Human

Application :

WB IHC

Recommended dilution :

WB 1:200-1000. IHC 1:50-200.

Subcellular location :

Cytoplasm

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the first reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.