Anti-GABRA1 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

GABRA1

Immunogen :

A synthetic peptide of human GABRA1

Synonym :

EJM;ECA4;EJM5

Isotype :

IgG

Gene ID :

2554

Clone No :

Swiss Port :

P14867

Molecular weight :

52kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB IHC

Recommended dilution :

WB 1:200-1000. IHC 1:25-100.

Subcellular location :

Cytoplasm

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene