Anti-CASP8AP2 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

CASP8AP2

Immunogen :

A synthetic peptide of human CASP8AP2

Synonym :

CED-4;FLASH;RIP25

Isotype :

IgG

Gene ID :

9994

Clone No :

Swiss Port :

Q9UKL3

Molecular weight :

223kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

WB IHC

Recommended dilution :

WB 1:8000-12000. IHC 1:10-100.

Subcellular location :

Cytoplasm Nucleus

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.