Anti-COL7A1 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

COL7A1

Immunogen :

A synthetic peptide of human COL7A1

Synonym :

EBD1;EBR1;EBDCT;NDNC8

Isotype :

IgG

Gene ID :

1294

Clone No :

Swiss Port :

Q02388

Molecular weight :

295kDa

Purification :

Affinity purification

Reactivity :

Human

Application :

WB

Recommended dilution :

WB 1:200-1000.

Subcellular location :

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen.