Anti-IFT74 Polyclonal Antibody

No :   K007696P
Size :   
Quantity :   
PRODUCT DESCRIPTION

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

IFT74

Immunogen :

A synthetic peptide of human IFT74

Synonym :

BBS20;CCDC2;CMG-1;CMG1

Isotype :

IgG

Gene ID :

80173

Clone No :

Swiss Port :

Q96LB3

Molecular weight :

69kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB

Recommended dilution :

WB 1:500-2000.

Subcellular location :

Cell projection Cytoplasmic vesicle cilium

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

Capillary morphogenesis protein 1 (CMG1), also known as intraflagellar transport protein 74 (ITP74) or coiled-coil domain-containing protein 2 (CCDC2), is a 600 amino acid human homologue of IFT-71, a complex B protein supporting intraflagellar transport (IFT) in Chlamydomonas. CMG1 localizes to the cytoplasmic vesicle and is highly expressed in adult and fetal kidney and testis, with lower levels of expression in adult heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. CMG1 has been suggested to have a role in the primary cilia of HUVEC, and it also functions as a transcriptional regulator of cyclin D2 in spermatocyte-derived cells.
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