Anti-CDK11A/CDK11B Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

CDK11A/CDK11B

Immunogen :

A synthetic peptide of human CDK11A/CDK11B

Synonym :

CDC2L2;CDC2L3;p58GTA;PITSLRE;CDK11-p46;CDK11-p58;CDK11-p110 / p58;PK58;CDK11;CLK-1;CDC2L1;p58CLK-1;CDK11-p46;CDK11-p58;p58CDC2L1;CDK11-p110

Isotype :

IgG

Gene ID :

728642/984

Clone No :

Swiss Port :

Q9UQ88/P21127

Molecular weight :

93kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

WB IHC

Recommended dilution :

WB 1:500-2000. IHC 1:25-100.

Subcellular location :

Cytoplasm

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

Cyclin-dependent kinases (CDKs) are a family of protein kinases first discovered for their role in regulating the cell cycle. They are also involved in regulating transcription, mRNA processing, and the differentiation of nerve cells. They are present in all known eukaryotes, and their regulatory function in the cell cycle has been evolutionarily conserved. CDKs are relatively small proteins, with molecular weights ranging from 34 to 40 kDa, and contain little more than the kinase domain. By definition, a CDK binds a regulatory protein called a cyclin. Without cyclin, CDK has little kinase activity; only the cyclin-CDK complex is an active kinase. CDKs phosphorylate their substrates on serines and threonines, so they are serine-threonine kinases.