Anti-TNFRSF8 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

TNFRSF8

Immunogen :

A synthetic peptide of human TNFRSF8

Synonym :

CD30;Ki-1;D1S166E

Isotype :

IgG

Gene ID :

943

Clone No :

Swiss Port :

P28908

Molecular weight :

64/14/51kDa

Purification :

Affinity purification

Reactivity :

Human

Application :

IHC

Recommended dilution :

IHC 1:25-100.

Subcellular location :

Cell membrane Cytoplasm Single-pass type I membrane protein

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.