Anti-NRG3 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

NRG3

Immunogen :

A synthetic peptide of human NRG3

Synonym :

HRG3;pro-NRG3

Isotype :

IgG

Gene ID :

10718

Clone No :

Swiss Port :

P56975

Molecular weight :

78kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

WB IHC

Recommended dilution :

WB 1:200-1000. IHC 1:50-200.

Subcellular location :

Cytoplasm

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4.