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Human c-KIT/CD117 Elisa Kit

Long Name: Stem Cell Factor Receptor
NO.:SEKH-0370
Quantity: 10

Information

Assay Type: Solid Phase Sandwich ELISA
Sensitivity: 11 pg/ml
Detection Range: 23.4-1500 pg/ml
Assay Length: 3.5h
Sample Type: Serum; Plasma; Cell culture supernatant.
Synonyms: KIT; C-Kit; CD117; PBT; SCFR;

Background

CD117, also known as c-kit and SCF R, is the cellular receptor for Stem Cell Factor (SCF), also named c-kit ligand, mast cell growth factor, and steel factor. This receptor-ligand system plays essential roles in germ cell development, melanogenesis, hematopoiesis, and oncogenesis. CD117 is expressed on lymphoid, myeloid, erythroid, and megakaryocyte progenitors, NK cells, germ cells, melanocytes, glial cells, vascular smooth muscle cells, placenta, and epithelial cells. Altered levels and mutations in CD117 are associated with several types of cancer including lung, breast, gastrointestinal stromal, and germ cell tumors.