Anti-TNIP3 Polyclonal Antibody

No :   K007570P
Size :   
Quantity :   
PRODUCT DESCRIPTION

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

TNIP3

Immunogen :

A synthetic peptide of human TNIP3

Synonym :

LIND;ABIN-3

Isotype :

IgG

Gene ID :

79931

Clone No :

Swiss Port :

Q96KP6

Molecular weight :

39kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

WB

Recommended dilution :

WB 1:500-2000.

Subcellular location :

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

TNIP3, which called LIND, that was upregulated in monocytes infected with Listeria monocytogenes. The predicted 325-amino acid protein contains 3 coiled-coil domains and is most likely localized to the nucleus. Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.
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