PRODUCT DESCRIPTION
Conjugation :
UnconjugateHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
TNIP3Immunogen :
A synthetic peptide of human TNIP3Synonym :
LIND;ABIN-3Isotype :
IgGGene ID :
79931Clone No :
Swiss Port :
Q96KP6Molecular weight :
39kDaPurification :
Affinity purificationReactivity :
Human MouseApplication :
WBRecommended dilution :
WB 1:500-2000.Subcellular location :
Storage :
Store at -20°C. Avoid freeze / thaw cycles.Background :
TNIP3, which called LIND, that was upregulated in monocytes infected with Listeria monocytogenes. The predicted 325-amino acid protein contains 3 coiled-coil domains and is most likely localized to the nucleus. Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.RELATED PRODUCTS
No data
REFERENCE LIBRARY
No data