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Human Osteoactivin/GPNMB Elisa Kit

Long Name: Glycoprotein Non-Metastatic Melanoma Protein B
Quantity: 10


Assay Type: Solid Phase Sandwich ELISA
Sensitivity: 60 pg/ml
Detection Range: 125-8,000 pg/ml
Assay Length: 3.5h
Sample Type: Serum; Plasma; Cell culture supernatant.
Synonyms: DC-HIL; Glycoprotein NMB; GPNMB; HGFIN;


Osteoactivin, also known as transmembrane glycoprotein NMB (GPNMB) and dendritic cell-associated transmembrane protein (DC-HIL), is a type I transmembrane glycoprotein that is found either on the plasma membrane or on membranes of the endosome/lysosome compartment. The extracellular region of Osteoactivin contains a heparin-binding motif and an integrin recognition RGD domain, while the cytocylasmic region contains an immunoreceptor tyrosine-based activation motif (ITAM) and lysosomal targeting motif.