Anti-PARD6A Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

PARD6A

Immunogen :

A synthetic peptide of human PARD6A

Synonym :

PAR6;PAR6C;TAX40;PAR-6A;TIP-40;PAR6alpha

Isotype :

IgG

Gene ID :

50855

Clone No :

Swiss Port :

Q9NPB6

Molecular weight :

37kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

IHC ELISA

Recommended dilution :

IHC 1:50-200. ELISA 1:2000-5000.

Subcellular location :

Cell junction Cell membrane Cell projection Cytoplasm ruffle tight junction

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.