Anti-IL2RA Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

IL2RA

Immunogen :

A synthetic peptide of human IL2RA

Synonym :

CD25;IL2R;TCGFR;IDDM10

Isotype :

IgG

Gene ID :

3559

Clone No :

Swiss Port :

P01589

Molecular weight :

31kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB ELISA

Recommended dilution :

WB 1:500-2000.

Subcellular location :

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.