Anti-IL15RA Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

IL15RA

Immunogen :

A synthetic peptide of human IL15RA

Synonym :

CD215;interleukin-15 receptor subunit alpha

Isotype :

IgG

Gene ID :

3601

Clone No :

Swiss Port :

Q13261

Molecular weight :

15-28kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

IHC ELISA

Recommended dilution :

IHC 1:50-200. ELISA 1:2000-5000.

Subcellular location :

Cytoplasm

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.