Anti-CRH Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

CRH

Immunogen :

A synthetic peptide of human CRH

Synonym :

CRF

Isotype :

IgG

Gene ID :

1392

Clone No :

Swiss Port :

P06850

Molecular weight :

21kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB IHC ELISA

Recommended dilution :

WB 1:200-1000. IHC 1: 25-100.

Subcellular location :

Cytoplasm Nucleus

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery.