Anti-CEBPA Polyclonal Antibody

No :   K007397P
Size :   
Quantity :   
PRODUCT DESCRIPTION

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

CEBPA

Immunogen :

A synthetic peptide of human CEBPA

Synonym :

CEBP;C/EBP-alpha

Isotype :

IgG

Gene ID :

1050

Clone No :

Swiss Port :

P49715

Molecular weight :

38kDa/36kDa/26kDa/41kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

IHC ELISA

Recommended dilution :

IHC 1: 50-100

Subcellular location :

Cytoplasm Nucleus

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
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