PRODUCT DESCRIPTION
Conjugation :
UnconjugateHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
CEBPAImmunogen :
A synthetic peptide of human CEBPASynonym :
CEBP;C/EBP-alphaIsotype :
IgGGene ID :
1050Clone No :
Swiss Port :
P49715Molecular weight :
38kDa/36kDa/26kDa/41kDaPurification :
Affinity purificationReactivity :
Human Mouse RatApplication :
IHC ELISARecommended dilution :
IHC 1: 50-100Subcellular location :
Cytoplasm NucleusStorage :
Store at -20°C. Avoid freeze / thaw cycles.Background :
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.RELATED PRODUCTS
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REFERENCE LIBRARY
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